Dual-Pathway Reactivation of NK Cells in Fibrotic Liver Disease

As liver fibrosis advances in MASH, NK cells lose their effectiveness—a decline closely tied to reduced STING signaling. This impairment weakens immune surveillance and accelerates disease progression. However, by simultaneously activating the STING and insulin pathways, NK cell function can be restored. Combined STING and insulin pathway activation may reinvigorate NK cells and enhance immunotherapeutic […]