GOOSE: Understanding and Designing Intrinsically Disordered Protein
We often read papers about the three-dimensional (3D) structures of proteins, particularly as rapidly evolving technologies such as cryo-EM, increasingly aided by AI, allow us to explore increasingly complex protein structures. However, not all proteins—or all regions within a protein—adopt a stable 3D structure. Some proteins, or specific regions of proteins, remain intrinsically disordered. These […]